Transdermal drug delivery and cutaneous metabolism

Research focus: Cutaneous metabolism and systemic delivery
Original source: https://stacks.cdc.gov/view/cdc/185709

Why it matters

A CDC-hosted review connecting transdermal delivery with metabolism occurring in the skin itself.

Key points

Skin can metabolize substances before they reach systemic circulation.
Models account for transport through the stratum corneum, viable epidermis, dermis, and cutaneous blood flow.
This helps explain why measurable skin penetration does not guarantee meaningful whole-body absorption.

Scope note: This is a research brief, not medical advice. It does not establish that soil minerals are nutritionally absorbed through intact skin.

Open the downloaded source snapshot