Essential oils and their constituents as skin penetration enhancer for transdermal drug delivery: a review

Research focus: Lipid disruption and penetration enhancement
Original source: https://pubmed.ncbi.nlm.nih.gov/25557808

Why it matters

A review of essential oils and their constituents as chemical penetration enhancers.

Key points

Some volatile oils interact with stratum-corneum lipids and proteins.
Those interactions can increase delivery of both lipophilic and hydrophilic compounds from a formulation.
The review also discusses toxicity and safety; “natural” does not mean harmless or appropriate for broken skin.

Scope note: This is a research brief, not medical advice. It does not establish that soil minerals are nutritionally absorbed through intact skin.

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