Absorption of chemicals through compromised skin

Research focus: Barrier damage and increased dermal uptake
Original source: https://pubmed.ncbi.nlm.nih.gov/19238423

Why it matters

A review of dermal absorption when the skin barrier is compromised. It is useful for distinguishing normal exposure through intact skin from exposure after abrasion, dermatitis, chemical irritation, or occupational damage.

Key points

Barrier impairment can increase uptake of chemicals already able to cross skin.
A damaged barrier may permit larger molecules or particles to enter more readily than intact skin.
The paper emphasizes that local toxicity and systemic absorption are separate outcomes that both matter.

Scope note: This is a research brief, not medical advice. It does not establish that soil minerals are nutritionally absorbed through intact skin.

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