Biophysical models for skin transport and absorption

Research focus: Diffusion models for drugs and environmental chemicals
Original source: https://stacks.cdc.gov/view/cdc/191990

Why it matters

A CDC/NIOSH-hosted review of biophysical models for skin transport and absorption.

Key points

Absorption is modeled as sequential movement through the stratum corneum, viable epidermis, and dermis.
The same modeling concepts support transdermal drug development and environmental chemical risk assessment.
Diffusion, partitioning, dose, vehicle, and skin condition are central variables.

Scope note: This is a research brief, not medical advice. It does not establish that soil minerals are nutritionally absorbed through intact skin.

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